I changed to every 5 days with 5 mg, but I kept lowering my dose (I was afraid of my endo forcing me onto a lower dose if my blood work showed too high E levels).

Something to think about in terms of your estradiol results is how long it’s been since your last injection. I’ve had several providers tell me they don’t care how long it’s been since my last injection, they just want to see. I push back that and only let them draw when it’s a true trough sample (e.g. I inject every 7 days, so I have blood drawn on that 7th day before I inject). This will give you (and your endo) a truer value to base your dosages/frequency on.

(bicalutamide didn’t seem to have any effect on my mood, positive or negative, so I stopped using it)

I had a similar experience to bicalutamide, but I kept taking it up until my orchiectomy. I tried spironolactone, but I didn’t like the results. If you’re not in the US, ask your doctor about cyproterone acetate. That stuff made me feel levelheaded; sadly because I was self medicating I had to stop when I began seeing a professional.

Another factor: I started HRT three months ago, so it could be that my body more easily slides back to testosterone right now and I just need to get over this initial transition to a new hormone regime.

This definitely sounds true. Based on my experiences, the first several months had ups and downs (hormone-wise). When those lows hit you, talk to a therapist, hangout with a friend, do a mini-fashion show in your room, go for a hike. The lows will pass; things definitely get easier. 💜

I used to have really bad mood swings that included lots of dysphoria. I made the soonest appointment with my doctor and brought this up to them. They changed the frequency of my injections to be closer together. This worked for me really well.

Alternatives could be different delivery methods like the patch or pills to help reduce the fluctuations in estradiol levels.

Stay strong girl friend 💜

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