I really enjoy Linux Mint and it is what I have been using for a while. Maybe give that a try if you have not already? If you want something with more up to date features and packages, maybe try Fedora. I have not really used it personally, but I am thinking of giving it a spin on one of my machines and seeing if I like it.

I am in a very similar situation with audio production. I have a lot of plugins and tried to see what I could get working with yabridge on my Linux laptop in my free time. Some stuff worked flawlessly, while a lot of other important plugins did not work at all. I hope that some day more stuff works and the tool gets more streamlined for less technical users, but for now it is not quite where it needs to be for my use case. In the mean time I switched to a DAW that has a Linux version (Bitwig) and I am slowly working towards switching to only using plugins that have a Linux version. I am far from a point where I can comfortably switch though, so for now Windows is an occupational hazard.

Stuff like this is the reason I built a NAS a few years ago.